Gasdermin E suppresses tumour growth by activating anti-tumour immunity
Cleavage of the gasdermin proteins to produce pore-forming amino-terminal fragments causes
inflammatory cell death (pyroptosis) 1 . Gasdermin E (GSDME, also known as DFNA5)—…
inflammatory cell death (pyroptosis) 1 . Gasdermin E (GSDME, also known as DFNA5)—…
Enhanced nitrogen deposition over China
China is experiencing intense air pollution caused in large part by anthropogenic emissions
of reactive nitrogen 1 , 2 . These emissions result in the deposition of atmospheric nitrogen (…
of reactive nitrogen 1 , 2 . These emissions result in the deposition of atmospheric nitrogen (…
Smad-dependent and Smad-independent pathways in TGF-β family signalling
R Derynck, YE Zhang - Nature, 2003 - nature.com
Transforming growth factor-β (TGF-β) proteins regulate cell function, and have key roles in
development and carcinogenesis. The intracellular effectors of TGF-β signalling, the Smad …
development and carcinogenesis. The intracellular effectors of TGF-β signalling, the Smad …
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
…, Q Sun, Z Ming, L Zhang, J Ge, L Zheng, Y Zhang… - Science, 2020 - science.org
A novel coronavirus [severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2)] outbreak
has caused a global coronavirus disease 2019 (COVID-19) pandemic, resulting in tens …
has caused a global coronavirus disease 2019 (COVID-19) pandemic, resulting in tens …
Mechanisms of Drug Resistance in Mycobacterium tuberculosis
Y Zhang, C Vilchèze… - Tuberculosis and the …, 2004 - Wiley Online Library
Drug resistance in tuberculosis (TB) is a particular problem because the lengthy therapy of
at least 6 months makes patient compliance very difficult, which frequently creates drug‐…
at least 6 months makes patient compliance very difficult, which frequently creates drug‐…
Delirium in the intensive care unit: occurrence and clinical course in older patients
OBJECTIVES: To describe the occurrence of delirium in a cohort of older medical intensive
care unit (ICU) patients and its short‐term duration in the hospital and to determine the …
care unit (ICU) patients and its short‐term duration in the hospital and to determine the …
[HTML][HTML] Transcriptional activators of TGF-β responses: Smads
Smads are a class of proteins that function as intracellular signaling effectors for the TGF-β
superfamily of secreted polypeptides. TGF-β-related factors regulate cell proliferation and …
superfamily of secreted polypeptides. TGF-β-related factors regulate cell proliferation and …
[HTML][HTML] A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)
…, XC Zhang, YW Zhang, YG Zhang, HM Zhang… - Military medical …, 2020 - Springer
In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province;
and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (…
and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (…
HMDB: the human metabolome database
…, M Gebremedhin, N Guo, Y Zhang… - Nucleic acids …, 2007 - academic.oup.com
The Human Metabolome Database (HMDB) is currently the most complete and comprehensive
curated collection of human metabolite and human metabolism data in the world. It …
curated collection of human metabolite and human metabolism data in the world. It …
[HTML][HTML] Non-Smad pathways in TGF-β signaling
YE Zhang - Cell research, 2009 - nature.com
Transforming growth factor-β utilizes a multitude of intracellular signaling pathways in
addition to Smads to regulate a wide array of cellular functions. These non-canonical, non-Smad …
addition to Smads to regulate a wide array of cellular functions. These non-canonical, non-Smad …