Background: Americans have a shorter life expectancy compared with residents of almost all
other high-income countries. We aim to estimate the impact of lifestyle factors on premature …

To address how the microbiome might modify the interaction between diet and cardiometabolic
health, we analyzed longitudinal microbiome data from 307 male participants in the …

Background The long-term health consequences of COVID-19 remain largely unclear. The
aim of this study was to describe the long-term health consequences of patients with COVID-…

Background The full range of long-term health consequences of COVID-19 in patients who
are discharged from hospital is largely unclear. The aim of our study was to comprehensively …

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of
Parkinson's disease. We created a LRRK2 transgenic mouse model that recapitulates cardinal …

Background : The associations between dietary saturated fats and the risk of coronary heart
disease (CHD) remain controversial, but few studies have compared saturated with …

Ciliary neurotrophic factor (CNTF) has a variety of actions within the nervous system. While
some of the actions of leukemia inhibitory factor (LIF) on neurons resemble those of CNTF, …

Importance Many changes in the economy, policies related to nutrition, and food processing
have occurred within the United States since 2000, and the net effect on dietary quality is …

Background: The optimal intake levels of fruit and vegetables for maintaining long-term
health are uncertain. Methods: We followed 66 719 women from the Nurses’ Health Study (1984–…

Importance Previous studies have shown distinct associations between specific dietary fat
and cardiovascular disease. However, evidence on specific dietary fat and mortality remains …