All species organize behaviors to optimally match daily changes in the environment, leading
to pronounced activity/rest cycles that track the light/dark cycle. Endogenous, approximately …

Sedentary activity is a modifiable life-style behavior and a key component in the etiology of
atherosclerotic cardiovascular disease (ACVD). US adults and children spend more than half …

… of doses to match the body’s natural daily rhythms and behavioral … ’s bioavailability and
duration of action through absorption, distribution, metabolism, and elimination. A medication’s …

Sitting time (ST) is associated with cardiovascular disease risk factors, whereas breaking ST
has been reported to be beneficial for reducing cardiovascular risk. Purpose: The objective …

Introduction It is unknown if there are limb differences in vascular function during prolonged
sitting. Purpose This study was designed to test whether the effects of prolonged sitting on …

The purpose of this study was to predict drug content and hardness of intact tablets using
artificial neural networks (ANN) and near-infrared spectroscopy (NIRS). Tablets for the drug …

… Once satisfactory images of near and far arterial walls were obtained, the transducer was
secured and stabilized in a stereotactic clamp, and landmarks were made on the subject’s …

A wealth of scientific knowledge is being generated in sleep and circadian science. In order
for us to realize the return on investment for such scientific knowledge and to improve the …

In humans, there is an endogenous, near 24-h (ie, circadian) variation in mood with the best
mood occurring during the circadian day and the worst mood occurring during the circadian …

Objective— Adverse cardiovascular events occur more frequently in the morning than at other
times of the day. Vascular endothelial function (VEF)—a robust cardiovascular risk marker…