[HTML][HTML] Applications of machine learning in animal behaviour studies

JJ Valletta, C Torney, M Kings, A Thornton, J Madden - Animal Behaviour, 2017 - Elsevier
In many areas of animal behaviour research, improvements in our ability to collect large and
detailed data sets are outstripping our ability to analyse them. These diverse, complex and …

[HTML][HTML] Repeated clinical malaria episodes are associated with modification of the immune system in children

Y Bediako, R Adams, AJ Reid, JJ Valletta, FM Ndungu… - BMC medicine, 2019 - Springer
Background There are over 200 million reported cases of malaria each year, and most
children living in endemic areas will experience multiple episodes of clinical disease before …

[HTML][HTML] Identification of immune signatures predictive of clinical protection from malaria

JJ Valletta, M Recker - PLoS computational biology, 2017 - journals.plos.org
Antibodies are thought to play an essential role in naturally acquired immunity to malaria.
Prospective cohort studies have frequently shown how continuous exposure to the malaria …

Gaussian process modelling of blood glucose response to free-living physical activity data in people with type 1 diabetes

JJ Valletta, AJ Chipperfield… - 2009 Annual International …, 2009 - ieeexplore.ieee.org
Good blood glucose control is important to people with type 1 diabetes to prevent diabetes-related
complications. Too much blood glucose (hyperglycaemia) causes long-term micro-…

Sentiment analysis of the Twitter response to Netflix's Our Planet documentary

…, U Cabuk, J Kryczka, B Trapp, JJ Valletta… - Conservation …, 2023 - Wiley Online Library
The role of nature documentaries in shaping public attitudes and behavior toward conservation
and wildlife issues is unclear. We analyzed the emotional content of over 2 million tweets …

Metabolic regulation during constant moderate physical exertion in extreme conditions in Type 1 diabetes

JJ Valletta, AJ Chipperfield, GF Clough… - Diabetic …, 2012 - Wiley Online Library
Metabolic regulation during constant moderate physical exertion in extreme conditions in
Type 1 diabetes - Valletta - 2012 - Diabetic Medicine - Wiley Online Library … JJ Valletta

[HTML][HTML] Comparison of whole blood and spleen transcriptional signatures over the course of an experimental malaria infection

…, Y Bediako, J Lin, J Joseph Valletta… - Scientific Reports, 2019 - nature.com
Although the spleen is broadly accepted as the major lymphoid organ involved in generating
immune responses to the erythrocytic stages of the malaria parasite, Plasmodium, human …

Multiscale immune selection and the transmission-diversity feedback in antigenically diverse pathogen systems

T Holding, JJ Valletta, M Recker - The American Naturalist, 2018 - journals.uchicago.edu
Antigenic diversity is commonly used by pathogens to enhance their transmission success.
Within-host clonal antigenic variation helps to maintain long infectious periods, whereas high …

[HTML][HTML] Individual-level variations in malaria susceptibility and acquisition of clinical protection

JJ Valletta, JWG Addy, AJ Reid, FM Ndungu… - Wellcome Open …, 2021 - ncbi.nlm.nih.gov
After decades of research, our understanding of when and why individuals infected with
Plasmodium falciparum develop clinical malaria is still limited. Correlates of immune protection …

Quantitative host resistance drives the evolution of increased virulence in an emerging pathogen

DE Gates, JJ Valletta, C Bonneaud… - Journal of evolutionary …, 2018 - academic.oup.com
Emergent infectious diseases can have a devastating impact on host populations. The high
selective pressures on both the hosts and the pathogens frequently lead to rapid adaptations …