The success of genome-wide association (GWA) studies for the detection of sequence
variation affecting complex traits in human has spurred interest in the use of large-scale high-…

The imprints of domestication and breed development on the genomes of livestock likely differ
from those of companion animals. A deep draft sequence assembly of shotgun reads from …

Background The dissection of complex traits of economic importance to the pig industry
requires the availability of a significant number of genetic markers, such as single nucleotide …

High-density single-nucleotide polymorphism (SNP) arrays have revolutionized the ability of
genome-wide association studies to detect genomic regions harboring sequence variants …

Background Genomic prediction of breeding values involves a so-called training analysis
that predicts the influence of small genomic regions by regression of observed information on …

We show that a commonly used statistic of genotypic diversity can be used to reflect one form
of deviation from panmixia, viz. clonal reproduction, by comparing observed and predicted …

The domestication and development of cattle has considerably impacted human societies,
but the histories of cattle breeds and populations have been poorly understood especially for …

Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in
or near segmental duplication regions are often intractable. Using a read depth approach …

Canine degenerative myelopathy (DM) is a fatal neurodegenerative disease prevalent in
several dog breeds. Typically, the initial progressive upper motor neuron spastic and general …

Population bottlenecks, inbreeding, and artificial selection can all, in principle, influence levels
of deleterious genetic variation. However, the relative importance of each of these effects …