User profiles for Jeff Hubbard

Jeffrey Hubbard

Centre for Integrative Genomics - University of Lausanne
Verified email at unil.ch
Cited by 652

Telavancin, a Multifunctional Lipoglycopeptide, Disrupts both Cell Wall Synthesis and Cell Membrane Integrity in Methicillin-Resistant Staphylococcus aureus

…, KM Krause, E Sandvik, JM Hubbard… - Antimicrobial agents …, 2005 - Am Soc Microbiol
The emergence and spread of multidrug-resistant gram-positive bacteria represent a serious
clinical problem. Telavancin is a novel lipoglycopeptide antibiotic that possesses rapid in …

[HTML][HTML] Rapid fast-delta decay following prolonged wakefulness marks a phase of wake-inertia in NREM sleep

J Hubbard, TC Gent, MMB Hoekstra… - Nature …, 2020 - nature.com
Sleep-wake driven changes in non-rapid-eye-movement sleep (NREM) sleep (NREMS) EEG
delta (δ-)power are widely used as proxy for a sleep homeostatic process. Here, we noted …

Non-circadian direct effects of light on sleep and alertness: lessons from transgenic mouse models

J Hubbard, E Ruppert, CM Gropp, P Bourgin - Sleep medicine reviews, 2013 - Elsevier
Light exerts a strong non-visual influence on human physiology and behavior. Additionally
light is known to affect sleep indirectly through the phase shifting of circadian rhythms, and …

[PDF][PDF] Intraspinal sensory neurons provide powerful inhibition to motor circuits ensuring postural control during locomotion

JM Hubbard, UL Böhm, A Prendergast, PEB Tseng… - Current Biology, 2016 - cell.com
In the vertebrate spinal cord, cerebrospinal fluid-contacting neurons (CSF-cNs) are GABAergic
neurons whose functions are only beginning to unfold. Recent evidence indicates that …

Sleep–wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex

…, M Jan, Y Emmenegger, J Hubbard… - Proceedings of the …, 2019 - National Acad Sciences
The timing and duration of sleep results from the interaction between a homeostatic sleep–wake-driven
process and a periodic circadian process, and involves changes in gene …

[PDF][PDF] Rocking promotes sleep in mice through rhythmic stimulation of the vestibular system

K Kompotis, J Hubbard, Y Emmenegger, A Perrault… - Current Biology, 2019 - cell.com
Rocking has long been known to promote sleep in infants and, more recently, also in adults,
increasing NREM sleep stage N2 and enhancing EEG slow waves and spindles. …

Mass media influences on public conceptions of social problems

JC Hubbard, ML DeFleur, LB DeFleur - Social Problems, 1975 - academic.oup.com
The present paper explores possible relationships between the mass media of communication
and social problems by three-way comparisons between the incidence of social problems …

[PDF][PDF] Optimization of a neurotoxin to investigate the contribution of excitatory interneurons to speed modulation in vivo

…, K Fidelin, J Gomez, H Ihara, Y Alcheikh, JM Hubbard… - Current Biology, 2016 - cell.com
Precise control of speed during locomotion is essential for adaptation of behavior in different
environmental contexts [1–4]. A central question in locomotion lies in understanding which …

Floppy eyelid syndrome is associated with obstructive sleep apnoea: a prospective study on 127 patients

J Chambe, S Laib, J Hubbard, C Erhardt… - Journal of sleep …, 2012 - Wiley Online Library
A few investigations have raised the question of a possible relationship between obstructive
sleep apnoea syndrome (OSAS) and floppy eyelid syndrome (FES). FES is an easily …

Cold-inducible RNA-binding protein (CIRBP) adjusts clock-gene expression and REM-sleep recovery following sleep deprivation

MMB Hoekstra, Y Emmenegger, J Hubbard, P Franken - Elife, 2019 - elifesciences.org
10.7554/eLife.43400.001 Sleep depriving mice affects clock-gene expression, suggesting
that these genes contribute to sleep homeostasis. The mechanisms linking extended …