We introduce a method for optically imaging intracellular proteins at nanometer spatial
resolution. Numerous sparse subsets of photoactivatable fluorescent protein molecules were …

We report a photoactivatable variant of theAequorea victoria green fluorescent protein (GFP)
that, after intense irradiation with 413-nanometer light, increases fluorescence 100 times …

Current fluorescent protein (FP) development strategies are focused on fine-tuning the
photophysical properties of blue to yellow variants derived from the Aequorea victoria jellyfish …

Chimeric antigen receptors (CARs) targeting CD19 have mediated dramatic antitumor
responses in hematologic malignancies, but tumor regression has rarely occurred using CARs …

The reliance of modern microscopy techniques on photoactivatable fluorescent proteins
prompted development of mCherry variants that are initially dark but become red fluorescent …

The ability to visualize, track, and quantify molecules and events in living cells with high spatial
and temporal resolution is essential for understanding biological systems. Only recently …

We have investigated properties relevant to quantitative imaging in living cells of five green
fluorescent protein (GFP) variants that have been used extensively or are potentially useful. …

Superresolution imaging is a rapidly emerging new field of microscopy that dramatically
improves the spatial resolution of light microscopy by over an order of magnitude (∼10–20-nm …

The cloning of the green fluorescent protein (GFP) from the jellyfish Aequoria victoria and its
expression in heterologous systems was a significant advance for optical microscopy of …

Photoactivatable fluorescent proteins (PA-FPs) are molecules that switch to a new fluorescent
state in response to activation to generate a high level of contrast. Over the past eight years…